Open AccessLoLoPicker: detecting low allelic-fraction variants from low-quality cancer samples
Author(s) -
Jian CarrotZhang,
Jacek Majewski
Publication year - 2017
Publication title -
oncotarget
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.373
H-Index - 127
ISSN - 1949-2553
DOI - 10.18632/oncotarget.16144
Subject(s) - allele , medicine , cancer , genetics , biology , computational biology , oncology , gene
Although several programs are designed to identify variants with low allelic-fraction, further improvement is needed, especially to push the detection limit of low allelic-faction variants in low-quality, "noisy" tumor samples.
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