Interaction between PPAR γ and SORL1 gene with Late-Onset Alzheimer’s disease in Chinese Han Population
Author(s) -
Hui Zhang,
Wei Zheng,
Linlin Hua,
Yutong Wang,
Jinfeng Li,
Hongying Bai,
Shanshan Wang,
Mingyao Du,
Xuelian Ma,
Chunyang Xu,
Xiaodong Li,
Bin Gong,
Yunliang Wang
Publication year - 2017
Publication title -
oncotarget
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.373
H-Index - 127
ISSN - 1949-2553
DOI - 10.18632/oncotarget.15691
Subject(s) - haplotype , multifactor dimensionality reduction , single nucleotide polymorphism , linkage disequilibrium , allele , minor allele frequency , genetics , locus (genetics) , allele frequency , biology , medicine , gene , genotype
To investigate the impact of sortilin-related receptor 1 gene 1 (SORL1) and peroxisome proliferator activated receptor gamma (PPAR G) gene single nucleotide polymorphisms (SNPs), gene- gene and gene- environment interactions and haplotype on late-onset Alzheimer's disease (LOAD) risk.
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