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Association of C5L2 genetic polymorphisms with coronary artery disease in a Han population in Xinjiang, China
Author(s) -
YingYing Zheng,
Xiang Xie,
Yitong Ma,
Zhen-Yan Fu,
Xiang Ma,
YiNing Yang,
XiaoMei Li,
Shuo Pan,
Dilare Adi,
BangDang Chen,
Fen Liu
Publication year - 2016
Publication title -
oncotarget
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.373
H-Index - 127
ISSN - 1949-2553
DOI - 10.18632/oncotarget.14353
Subject(s) - single nucleotide polymorphism , coronary artery disease , medicine , confidence interval , genotype , population , gastroenterology , case control study , cardiology , biology , gene , genetics , environmental health
C5aR-like receptor 2 (C5L2) has been identified as a receptor for the inflammatory factor Complement 5a (C5a) and acylation-stimulating protein (ASP). ASP binding to C5L2 leading to a net accumulation of TG stores and glucose transporter. The aim of the present study is to evaluate the association of the SNPs of C5L2 gene with coronary artery disease (CAD) in a Chinese population.

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