Charcot-Marie-Tooth gene, SBF2, associated with taxane-induced peripheral neuropathy in African Americans | Zendy

Bryan P. Schneider | Zendy; Dongbing Lai | Zendy; Fei Shen | Zendy; Guanglong Jiang | Zendy; Milan Radovich | Zendy; Lang Li | Zendy; Laura Gardner | Zendy; Kathy D. Miller | Zendy; Anne O’Neill | Zendy; Joseph A. Sparano | Zendy; Gloria Xue | Zendy; Tatiana Foroud | Zendy; George W. Sledge | Zendy

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Charcot-Marie-Tooth gene, SBF2, associated with taxane-induced peripheral neuropathy in African Americans

Author(s) -

Bryan P. Schneider,

Dongbing Lai,

Fei Shen,

Guanglong Jiang,

Milan Radovich,

Lang Li,

Laura Gardner,

Kathy D. Miller,

Anne O’Neill,

Joseph A. Sparano,

Gloria Xue,

Tatiana Foroud,

George W. Sledge

Publication year - 2016

Publication title -

oncotarget

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.373

H-Index - 127

ISSN - 1949-2553

DOI - 10.18632/oncotarget.12545

Subject(s) - medicine , peripheral neuropathy , oncology , exome , palb2 , cancer , allele , germline mutation , genetics , gene , bioinformatics , biology , phenotype , mutation , exome sequencing , endocrinology , diabetes mellitus

Taxane-induced peripheral neuropathy (TIPN) is one of the most important survivorship issues for cancer patients. African Americans (AA) have previously been shown to have an increased risk for this toxicity. Germline predictive biomarkers were evaluated to help identify a priori which patients might be at extraordinarily high risk for this toxicity.

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