Individual patient oesophageal cancer 3D models for tailored treatment | Zendy

J. Saunders | Zendy; David Onion | Zendy; Pamela Collier | Zendy; Matthew S. Dorrington | Zendy; Richard H. Argent | Zendy; Philip A. Clarke | Zendy; Alexander M. Reece-Smith | Zendy; Simon L. Parsons | Zendy; Anna M. Grabowska | Zendy

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Individual patient oesophageal cancer 3D models for tailored treatment

Author(s) -

J. Saunders,

David Onion,

Pamela Collier,

Matthew S. Dorrington,

Richard H. Argent,

Philip A. Clarke,

Alexander M. Reece-Smith,

Simon L. Parsons,

Anna M. Grabowska

Publication year - 2016

Publication title -

oncotarget

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.373

H-Index - 127

ISSN - 1949-2553

DOI - 10.18632/oncotarget.12500

Subject(s) - medicine , chemotherapy , cancer , mesenchymal stem cell , cancer cell , panobinostat , in vivo , stromal cell , oncology , cancer research , clinical trial , pathology , biology , biochemistry , microbiology and biotechnology , histone deacetylase , gene , histone

A model to predict chemotherapy response would provide a marked clinical benefit, enabling tailored treatment of oesophageal cancer, where less than half of patients respond to the routinely administered chemotherapy.

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