The importance of tissue confirmation of metastatic disease in patients with breast cancer: lesson from a brain metastasis case | Zendy

Jingxian Ding | Zendy; Pinghua Hu | Zendy; Jun Chen | Zendy; Xiaobo Wu | Zendy; Yali Cao | Zendy

Open Access

The importance of tissue confirmation of metastatic disease in patients with breast cancer: lesson from a brain metastasis case

Author(s) -

Jingxian Ding,

Pinghua Hu,

Jun Chen,

Xiaobo Wu,

Yali Cao

Publication year - 2016

Publication title -

oncoscience

Language(s) - English

Resource type - Journals

ISSN - 2331-4737

DOI - 10.18632/oncoscience.320

Subject(s) - medicine , breast cancer , trastuzumab , oncology , brain metastasis , hormonal therapy , radiation therapy , metastasis , cancer , mastectomy , chemotherapy , estrogen receptor , tamoxifen , pathology

The discrepancy of estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2) statuses in breast cancers has been reported. Available systemic therapy for patients with breast cancer is based on the molecular subtypes as identified by IHC and/or FISH. However, these biomarkers may change throughout tumor progression.

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