Open AccessA predictive signature for therapy assignment and risk assessment in prostate cancer
Author(s) -
Désirée Bonci,
Ruggero De Maria
Publication year - 2015
Publication title -
oncoscience
Language(s) - English
Resource type - Journals
ISSN - 2331-4737
DOI - 10.18632/oncoscience.271
Subject(s) - prostate cancer , cancer , prostate , oncology , medicine , signature (topology) , risk assessment , computer science , computer security , geometry , mathematics
Prostate cancer remains the second leading cause of death in men. It is imperative to improve patient management in identifying bio-markers for personalized treatment. We demonstrated miR-15/miR-16 loss and miR-21 up-regulation and deregulation of their target genes, which represent a promising signature for ameliorating therapy assignment and risk assessment in prostate cancer.
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