The taxonomy of brain cancer stem cells: what's in a name?
Author(s) -
David H. Gutmann
Publication year - 2014
Publication title -
oncoscience
Language(s) - English
Resource type - Journals
ISSN - 2331-4737
DOI - 10.18632/oncoscience.25
Subject(s) - stem cell , neuroscience , cancer stem cell , brain cancer , perspective (graphical) , neural stem cell , biology , cancer , psychology , computer science , microbiology and biotechnology , genetics , artificial intelligence
With the increasing recognition that stem cells play vital roles in the formation, maintenance, and potential targeted treatment of brain tumors, there has been an exponential increase in basic laboratory and translational research on these cell types. However, there are several different classes of stem cells germane to brain cancer, each with distinct capabilities and functions. In this perspective, we discuss the types of stem cells relevant to brain tumor pathogenesis, and suggest a nomenclature for future preclinical and clinical investigation.
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