LncRNA PVT1 accelerates malignant phenotypes of bladder cancer cells by modulating miR-194-5p/BCLAF1 axis as a ceRNA | Zendy

Mingwei Chen | Zendy; Rongyuan Zhang | Zendy; Le Lu | Zendy; Jian Du | Zendy; Chunyang Chen | Zendy; Keke Ding | Zendy; Xuedong Wei | Zendy; Guangbo Zhang | Zendy; Yuhua Huang | Zendy; Jianquan Hou | Zendy

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LncRNA PVT1 accelerates malignant phenotypes of bladder cancer cells by modulating miR-194-5p/BCLAF1 axis as a ceRNA

Author(s) -

Mingwei Chen,

Rongyuan Zhang,

Le Lu,

Jian Du,

Chunyang Chen,

Keke Ding,

Xuedong Wei,

Guangbo Zhang,

Yuhua Huang,

Jianquan Hou

Publication year - 2020

Publication title -

aging

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.473

H-Index - 90

ISSN - 1945-4589

DOI - 10.18632/aging.202203

Subject(s) - phenotype , pvt1 , bladder cancer , competing endogenous rna , cancer research , biology , cancer , oncology , medicine , gene , genetics , long non coding rna , downregulation and upregulation

Numerous studies proved that long non-coding RNA (lncRNA) is involved in the progression of multifarious diseases, especially in some carcinomas. As a potential tumor biomarker, plasmacytoma variant translocation 1 gene (PVT1) is involved in the development and progression of multifarious cancers. Nevertheless, the intrinsic and concrete molecular mechanism of PVT1 in bladder cancer still remained unclear, which is also the dilemma faced in many non-coding RNA studies.

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