Hyperbaric oxygen therapy increases telomere length and decreases immunosenescence in isolated blood cells : a prospective trial | Zendy

Yafit Hachmo | Zendy; Amir Hadanny | Zendy; Ramzia Abu Hamed | Zendy; Malka Daniel-Kotovsky | Zendy; Merav Catalogna | Zendy; Gregory Fishlev | Zendy; Erez Lang | Zendy; Nir Polak | Zendy; Keren Doenyas | Zendy; Mony Friedman | Zendy; Yonatan Zemel | Zendy; Yair Bechor | Zendy; Shai Efrati | Zendy

Open Access

Hyperbaric oxygen therapy increases telomere length and decreases immunosenescence in isolated blood cells : a prospective trial

Author(s) -

Yafit Hachmo,

Amir Hadanny,

Ramzia Abu Hamed,

Malka Daniel-Kotovsky,

Merav Catalogna,

Gregory Fishlev,

Erez Lang,

Nir Polak,

Keren Doenyas,

Mony Friedman,

Yonatan Zemel,

Yair Bechor,

Shai Efrati

Publication year - 2020

Publication title -

aging

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.473

H-Index - 90

ISSN - 1945-4589

DOI - 10.18632/aging.202188

Subject(s) - immunosenescence , telomere , medicine , biology , immunology , dna , immune system , genetics

Aging is characterized by the progressive loss of physiological capacity. At the cellular level, two key hallmarks of the aging process include telomere length (TL) shortening and cellular senescence. Repeated intermittent hyperoxic exposures, using certain hyperbaric oxygen therapy (HBOT) protocols, can induce regenerative effects which normally occur during hypoxia. The aim of the current study was to evaluate whether HBOT affects TL and senescent cell concentrations in a normal, non-pathological, aging adult population.

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