Open AccessEffect of lncRNA WT1-AS regulating WT1 on oxidative stress injury and apoptosis of neurons in Alzheimer's disease via inhibition of the miR-375/SIX4 axis
Author(s) -
Quanbao Wang,
Xiumin Ge,
Jie Zhang,
Licheng Chen
Publication year - 2020
Publication title -
aging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.473
H-Index - 90
ISSN - 1945-4589
DOI - 10.18632/aging.104079
Subject(s) - oxidative stress , apoptosis , disease , microbiology and biotechnology , oxidative phosphorylation , neuroscience , cancer research , biology , medicine , endocrinology , genetics , biochemistry
To study the effect of lncRNA WT1-AS on oxidative stress injury (OSI) and apoptosis of neurons in Alzheimer's disease (AD) and its specific mechanisms related to the microRNA-375 (miR-375)/SIX4 axis and WT1 expression.
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