Open AccessMolecular subtypes based on DNA promoter methylation predict prognosis in lung adenocarcinoma patients
Author(s) -
Shanping Shi,
Mingjun Xu,
Xi Yang
Publication year - 2020
Publication title -
aging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.473
H-Index - 90
ISSN - 1945-4589
DOI - 10.18632/aging.104062
Subject(s) - dna methylation , adenocarcinoma , methylation , lung cancer , cancer research , lung , biology , dna , oncology , medicine , computational biology , genetics , gene , cancer , gene expression
The heterogeneity of lung adenocarcinoma (LADC) makes the early diagnosis and treatment of the disease difficult. Gene silencing of DNA methylation is an important mechanism of tumorigenesis. A combination of methylation and clinical features can improve the classification of LADC heterogeneity.
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