Umbilical cord mesenchymal stem cells protect thymus structure and function in aged C57 mice by downregulating aging-related genes and upregulating autophagy- and anti-oxidative stress-related genes | Zendy

Xinghua Pan | Zendy; Qing-Keng Lin | Zendy; Xiang Yao | Zendy; ZiAn Li | Zendy; Xuemin Cai | Zendy; Rongqing Pang | Zendy; GuangPing Ruan | Zendy

Open Access

Umbilical cord mesenchymal stem cells protect thymus structure and function in aged C57 mice by downregulating aging-related genes and upregulating autophagy- and anti-oxidative stress-related genes

Author(s) -

Xinghua Pan,

Qing-Keng Lin,

Xiang Yao,

ZiAn Li,

Xuemin Cai,

Rongqing Pang,

GuangPing Ruan

Publication year - 2020

Publication title -

aging

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.473

H-Index - 90

ISSN - 1945-4589

DOI - 10.18632/aging.103594

Subject(s) - senescence , biology , mesenchymal stem cell , transplantation , regeneration (biology) , cd8 , stem cell , oxidative stress , andrology , endocrinology , microbiology and biotechnology , immunology , medicine , immune system

To study the effect of allogeneic umbilical cord mesenchymal stem cell transplantation on the structure and function of the thymus in aged C57 mice and provide a new method for the treatment of senile thymic atrophy.

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