Bioinformatics profiling integrating a four immune-related long non-coding RNAs signature as a prognostic model for papillary renal cell carcinoma
Author(s) -
Yu Liu,
Xin Gou,
Zongjie Wei,
Haitao Yu,
Xiang Zhou,
Xinyuan Li
Publication year - 2020
Publication title -
aging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.473
H-Index - 90
ISSN - 1945-4589
DOI - 10.18632/aging.103580
Subject(s) - papillary renal cell carcinomas , renal cell carcinoma , immune system , gene expression profiling , medicine , biology , computational biology , bioinformatics , cancer research , oncology , gene , immunology , gene expression , genetics
Papillary renal cell carcinoma (pRCC) was the 2 nd most common subtype, accounting for approximately 15% incidence of renal cell carcinoma (RCC). Immune related long non-coding RNAs (IR-lncRs) plentiful in immune cells and immune microenvironment (IME) are potential in evaluating prognosis and assessing the effects of immunotherapy. A completed and meaningful IR-lncRs analysis based on abundant pRCC gene samples from The Cancer Genome Atlas (TCGA) will provide insight in this field.
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