Open AccessInhibition of Exo-miR-19a-3p derived from cardiomyocytes promotes angiogenesis and improves heart function in mice with myocardial infarction via targeting HIF-1α
Author(s) -
Lianping Gou,
Cheng Xue,
Xiaoyan Tang,
Zhiyuan Fang
Publication year - 2020
Publication title -
aging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.473
H-Index - 90
ISSN - 1945-4589
DOI - 10.18632/aging.103563
Subject(s) - angiogenesis , myocardial infarction , cardiology , medicine , function (biology) , infarction , biology , microbiology and biotechnology
Myocardial infarction (MI), a common presentation for cardiovascular disease, is caused by reduction of blood flow and oxygen supply and is one of the main causes of death worldwide. MicroRNAs participate in multiple physiological and pathological processed and play crucial role in myocardial infarction.
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