Construction of a prognosis-predicting model based on autophagy-related genes for hepatocellular carcinoma (HCC) patients | Zendy

Yayun Zhu | Zendy; Ru Wang | Zendy; Wanbin Chen | Zendy; Qiuyu Chen | Zendy; Jian Zhou | Zendy

Open Access

Construction of a prognosis-predicting model based on autophagy-related genes for hepatocellular carcinoma (HCC) patients

Author(s) -

Yayun Zhu,

Ru Wang,

Wanbin Chen,

Qiuyu Chen,

Jian Zhou

Publication year - 2020

Publication title -

aging

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.473

H-Index - 90

ISSN - 1945-4589

DOI - 10.18632/aging.103507

Subject(s) - hepatocellular carcinoma , autophagy , gene , oncology , medicine , carcinoma , cancer research , biology , genetics , apoptosis

Autophagy, a highly conserved cellular catabolic process by which the eukaryotic cells deliver autophagosomes engulfing cellular proteins and organelles to lysosomes for degradation, is critical for maintaining cellular homeostasis in response to various signals and nutrient stresses. The dysregulation of autophagy has been noted in the pathogenesis of cancers. Our study aims to investigate the prognosis-predicting value of autophagy-related genes (ARG) in hepatocellular carcinoma (HCC).

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