Open AccessmiR-125a-5p inhibits glycolysis by targeting hexokinase-II to improve pulmonary arterial hypertension
Author(s) -
Li Luo,
Lusheng Xiao,
Guili Lian,
Huajun Wang,
Liangdi Xie
Publication year - 2020
Publication title -
aging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.473
H-Index - 90
ISSN - 1945-4589
DOI - 10.18632/aging.103163
Subject(s) - hexokinase , glycolysis , cardiology , pulmonary hypertension , medicine , chemistry , metabolism
The aim of this study was to investigate the effect of microRNAs on the proliferation of pulmonary arterial smooth muscle cells (PASMCs) as a result of targeting hexokinase-II (HK-II) and its mechanism of action.
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