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Pluronic P123 modified nano micelles loaded with doxorubicin enhanced tumor-suppressing effect on drug-resistant breast cancer cells
Author(s) -
Xiaoyu Zhang,
Weibin Chen,
Jie Bai,
Lijun Jin,
Xiaoning Kang,
Hui Zhang,
Zunyi Wang
Publication year - 2020
Publication title -
aging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.473
H-Index - 90
ISSN - 1945-4589
DOI - 10.18632/aging.103138
Subject(s) - poloxamer , doxorubicin , micelle , nano , breast cancer , drug , metastatic breast cancer , pharmacology , cancer , medicine , chemistry , materials science , chemotherapy , copolymer , polymer , organic chemistry , aqueous solution , composite material
Nano micelles (NMs) have been widely used for various biomedical applications due to its unique physiochemical properties. This study aimed to investigated the anti-tumor effect of doxorubicin (Dox)-loaded Pluronic P123 (P123) and PEG2000-DSPE mixed NMs in drug-resistant breast cancer cells.

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