Pluronic P123 modified nano micelles loaded with doxorubicin enhanced tumor-suppressing effect on drug-resistant breast cancer cells
Author(s) -
Xiaoyu Zhang,
Weibin Chen,
Jie Bai,
Lijun Jin,
Xiaoning Kang,
Hui Zhang,
Zunyi Wang
Publication year - 2020
Publication title -
aging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.473
H-Index - 90
ISSN - 1945-4589
DOI - 10.18632/aging.103138
Subject(s) - poloxamer , doxorubicin , micelle , nano , breast cancer , drug , metastatic breast cancer , pharmacology , cancer , medicine , chemistry , materials science , chemotherapy , copolymer , polymer , organic chemistry , aqueous solution , composite material
Nano micelles (NMs) have been widely used for various biomedical applications due to its unique physiochemical properties. This study aimed to investigated the anti-tumor effect of doxorubicin (Dox)-loaded Pluronic P123 (P123) and PEG2000-DSPE mixed NMs in drug-resistant breast cancer cells.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom