Open AccessHDAC6 promotes sepsis development by impairing PHB1-mediated mitochondrial respiratory chain function
Author(s) -
Shi-Dong Guo,
Shengtao Yan,
Wen Li,
Hong Zhou,
Jianping Yang,
Yao Yao,
Mei-Jia Shen,
Liuwei Zhang,
Hongbo Zhang,
Lichao Sun
Publication year - 2020
Publication title -
aging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.473
H-Index - 90
ISSN - 1945-4589
DOI - 10.18632/aging.102964
Subject(s) - sepsis , oxidative stress , hdac6 , western blot , biology , mitochondrion , blot , histone , microbiology and biotechnology , immunology , histone deacetylase , biochemistry , gene
This study was aimed at investigating the regulation of mitochondrial function by histone deacetylase 6 (HDAC6) and the role of HDAC6 in the development and progression of sepsis.
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