Open AccessLncRNA AGAP2-AS1 augments cell viability and mobility, and confers gemcitabine resistance by inhibiting miR-497 in colorectal cancer
Author(s) -
Sen Hong,
Zhenkun Yan,
Yumei Song,
Miaomiao Bi,
Shiquan Li
Publication year - 2020
Publication title -
aging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.473
H-Index - 90
ISSN - 1945-4589
DOI - 10.18632/aging.102940
Subject(s) - cancer research , cell growth , antisense rna , carcinogenesis , biology , colorectal cancer , cancer , rna , gene , genetics
Most recently, long non-coding RNAs (lncRNAs) emerge as crucial modulators in many biological processes, such as embryonic development, cell growth, and tumorigenesis. However, the correlations between lncRNAs and colorectal cancer (CRC) cell proliferation, metastasis, and gemcitabine resistance are not well understood.
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