Long non-coding RNA RHPN1-AS1 promotes tumorigenesis and metastasis of ovarian cancer by acting as a ceRNA against miR-596 and upregulating LETM1
Author(s) -
Junrong Wang,
Weimin Ding,
Yingke Xu,
Enfu Tao,
Miaojun Mo,
Wei Xu,
Cai Xu,
Xiaohong Chen,
Junhui Yuan,
Xiuying Wu
Publication year - 2020
Publication title -
aging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.473
H-Index - 90
ISSN - 1945-4589
DOI - 10.18632/aging.102911
Subject(s) - competing endogenous rna , cancer research , long non coding rna , biology , carcinogenesis , ovarian cancer , metastasis , downregulation and upregulation , pi3k/akt/mtor pathway , protein kinase b , in vivo , malat1 , cancer , signal transduction , microbiology and biotechnology , gene , genetics , biochemistry
In recent decades, long non-coding RNAs (lncRNAs) have been reported as crucial functional regulators involved in ovarian cancer. In the present study, we explored how lncRNA RHPN1-AS1 influences the progression of epithelial ovarian cancer (EOC) through tumor cell-dependent mechanisms.
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