Open AccessESHRD: deconvolution of brain homogenate RNA expression data to identify cell-type-specific alterations in Alzheimer’s disease
Author(s) -
Ignazio S. Piras,
Christiane Bleul,
Joshua S. Talboom,
Matthew De Both,
Isabelle Schrauwen,
Glenda M. Halliday,
Amanda Myers,
Geidy E. Serrano,
Thomas G. Beach,
Matthew J. Huentelman
Publication year - 2020
Publication title -
aging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.473
H-Index - 90
ISSN - 1945-4589
DOI - 10.18632/aging.102840
Subject(s) - cell type , biology , gene expression , gene , cell , gene expression profiling , rna , angiogenesis , computational biology , neuroscience , cancer research , genetics
We describe herein a bioinformatics approach that leverages gene expression data from brain homogenates to derive cell-type specific differential expression results.
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