Inhibition of miR-193a-3p protects human umbilical vein endothelial cells against intermittent hypoxia-induced endothelial injury by targeting FAIM2
Author(s) -
Qingshi Chen,
Guofu Lin,
JianChai Huang,
LiDa Chen,
Yibin Liu,
Jiefeng Huang,
Shuyi Zhang
Publication year - 2020
Publication title -
aging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.473
H-Index - 90
ISSN - 1945-4589
DOI - 10.18632/aging.102729
Subject(s) - umbilical vein , apoptosis , viability assay , hypoxia (environmental) , microrna , intermittent hypoxia , blot , medicine , cancer research , chemistry , microbiology and biotechnology , biology , obstructive sleep apnea , gene , in vitro , biochemistry , organic chemistry , oxygen
The functions and molecular regulatory mechanisms of miR-193a-3p in cardiac injury induced by obstructive sleep apnea (OSA) are poorly understood. This study aimed to explore the role of miR-193a-3p in intermittent hypoxia(IH)-induced human umbilical vein endothelial cells (HUVECs) injury.
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