Relationship between PD-L1 expression and 18F-FDG uptake in gastric cancer | Zendy

Ruohua Chen | Zendy; Yumei Chen | Zendy; Gang Huang | Zendy; Jianjun Liu | Zendy

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Relationship between PD-L1 expression and 18F-FDG uptake in gastric cancer

Author(s) -

Ruohua Chen,

Yumei Chen,

Gang Huang,

Jianjun Liu

Publication year - 2019

Publication title -

aging

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.473

H-Index - 90

ISSN - 1945-4589

DOI - 10.18632/aging.102567

Subject(s) - medicine , cancer , tumor infiltrating lymphocytes , immunotherapy , oncology , pd l1 , multivariate analysis , cancer immunotherapy

Immunotherapy has been successfully utilized for treatment of gastric cancer, so the identification of clinicopathologic features that are predictive of response to this therapy is crucial. 18 F-FDG PET/CT can provide information on the molecular phenotype of many malignant tumors. The correlation between 18 F-FDG accumulation and PD-L1/PD-L1-TILs status in gastric cancer patients has not been investigated. The aim of the current study is to assess whether 18 F-FDG accumulation is associated with PD-L1/PD-L1-TILs status, and whether 18 F-FDG PET/CT may be useful for predicting PD-L1/PD-L1-TILs expression of gastric cancer.

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