Adipose-derived stem cells contribute to cardiovascular remodeling
Author(s) -
Hui Ni,
Yiming Zhao,
Yongli Ji,
Jian Shen,
Meixiang Xiang,
Yao Xie
Publication year - 2019
Publication title -
aging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.473
H-Index - 90
ISSN - 1945-4589
DOI - 10.18632/aging.102491
Subject(s) - adipose tissue , paracrine signalling , mesenchymal stem cell , stem cell , biology , microbiology and biotechnology , pathology , bioinformatics , medicine , endocrinology , receptor , genetics
Obesity is an independent risk factor for cardiovascular disease. Adipose tissue was initially thought to be involved in metabolism through paracrine. Recent researches discovered mesenchymal stem cells inside adipose tissue which could differentiate into vascular lineages in vitro and in vivo , participating vascular remodeling. However, there were few researches focusing on distinct characteristics and functions of adipose-derived stem cells (ADSCs) from different regions. This is the first comprehensive review demonstrating the variances of ADSCs from the perspective of their origins.
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