Selected by gene co-expression network and molecular docking analyses, ENMD-2076 is highly effective in glioblastoma-bearing rats
Author(s) -
Sheng Zhong,
Yang Bai,
Bo Wu,
Junliang Ge,
Shanshan Jiang,
Weihang Li,
Xinhui Wang,
Junan Ren,
Haiyang Xu,
Yong Chen,
Gang Zhao
Publication year - 2019
Publication title -
aging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.473
H-Index - 90
ISSN - 1945-4589
DOI - 10.18632/aging.102422
Subject(s) - in vivo , glioblastoma , cancer research , oncogene , pi3k/akt/mtor pathway , in vitro , kegg , biology , apoptosis , cell cycle , osteosarcoma , gene , gene expression , transcriptome , genetics
Glioblastoma is the most common type of malignant brain tumor. Bioinformatics technology and structure biology were effectively and systematically used to identify specific targets in malignant tumors and screen potential drugs.
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