Identifying hub genes of clear cell renal cell carcinoma associated with the proportion of regulatory T cells by weighted gene co-expression network analysis | Zendy

YeHui Chen | Zendy; ShaoHao Chen | Zendy; Jian Hou | Zendy; ZhiBin Ke | Zendy; YuPeng Wu | Zendy; Tingting Lin | Zendy; Yong Wei | Zendy; XueYi Xue | Zendy; QingShui Zheng | Zendy; JinBei Huang | Zendy; Ning Xu | Zendy

Open Access

Identifying hub genes of clear cell renal cell carcinoma associated with the proportion of regulatory T cells by weighted gene co-expression network analysis

Author(s) -

YeHui Chen,

ShaoHao Chen,

Jian Hou,

ZhiBin Ke,

YuPeng Wu,

Tingting Lin,

Yong Wei,

XueYi Xue,

QingShui Zheng,

JinBei Huang,

Ning Xu

Publication year - 2019

Publication title -

aging

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.473

H-Index - 90

ISSN - 1945-4589

DOI - 10.18632/aging.102397

Subject(s) - immunotherapy , clear cell renal cell carcinoma , immune system , gene , biology , cancer research , computational biology , renal cell carcinoma , gene regulatory network , cancer immunotherapy , cancer , cell , gene expression , immunology , medicine , oncology , genetics

Numerous patients with clear cell renal cell carcinoma (ccRCC) experience drug resistance after immunotherapy. Regulatory T (Treg) cells may work as a suppressor for anti-tumor immune response.

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