Up regulation of Rho-associated coiled-coil containing kinase1 (ROCK1) is associated with genetic instability and poor prognosis in prostate cancer | Zendy

Stefan Steurer | Zendy; Benjamin Hager | Zendy; Franziska Büscheck | Zendy; Doris Höflmayer | Zendy; Maria Christina Tsourlakis | Zendy; Sarah Minner | Zendy; Till S. Clauditz | Zendy; Claudia HubeMagg | Zendy; Andreas M. Luebke | Zendy; Ronald Simon | Zendy; Jakob R. Izbicki | Zendy; Eike Burandt | Zendy; Guido Sauter | Zendy; Christoph Fraune | Zendy; Sören Weidemann | Zendy; Thorsten Schlomm | Zendy; Hans Heinzer | Zendy; Alexander Haese | Zendy; Markus Graefen | Zendy; Hartwig Huland | Zendy; Asmus Heumann | Zendy

Open Access

Up regulation of Rho-associated coiled-coil containing kinase1 (ROCK1) is associated with genetic instability and poor prognosis in prostate cancer

Author(s) -

Stefan Steurer,

Benjamin Hager,

Franziska Büscheck,

Doris Höflmayer,

Maria Christina Tsourlakis,

Sarah Minner,

Till S. Clauditz,

Claudia HubeMagg,

Andreas M. Luebke,

Ronald Simon,

Jakob R. Izbicki,

Eike Burandt,

Guido Sauter,

Christoph Fraune,

Sören Weidemann,

Thorsten Schlomm,

Hans Heinzer,

Alexander Haese,

Markus Graefen,

Hartwig Huland,

Asmus Heumann

Publication year - 2019

Publication title -

aging

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.473

H-Index - 90

ISSN - 1945-4589

DOI - 10.18632/aging.102294

Subject(s) - prostate cancer , pten , rock1 , cancer , cancer research , prostate , erg , medicine , biology , oncology , kinase , pi3k/akt/mtor pathway , protein kinase a , signal transduction , genetics , retinal , ophthalmology

Overexpression of the cytoskeleton-modulating kinase ROCK1 has been associated with unfavorable outcome in many cancers, but its impact in prostate cancer is largely unknown.

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