Elevated kindlin-2 promotes tumour progression and angiogenesis through the mTOR/VEGFA pathway in melanoma | Zendy

Chuanyuan Wei | Zendy; Meng-Xuan Zhu | Zendy; Pengfei Zhang | Zendy; Xuan Yang | Zendy; Lu Wang | Zendy; Jianghui Ying | Zendy; Wenjie Luan | Zendy; Cheng Chen | Zendy; Jiaqi Liu | Zendy; Zhu Ming | Zendy; Yanwen Yang | Zendy; Zihao Feng | Zendy; Fazhi Qi | Zendy; Jianying Gu | Zendy

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Elevated kindlin-2 promotes tumour progression and angiogenesis through the mTOR/VEGFA pathway in melanoma

Author(s) -

Chuanyuan Wei,

Meng-Xuan Zhu,

Pengfei Zhang,

Xuan Yang,

Lu Wang,

Jianghui Ying,

Wenjie Luan,

Cheng Chen,

Jiaqi Liu,

Zhu Ming,

Yanwen Yang,

Zihao Feng,

Fazhi Qi,

Jianying Gu

Publication year - 2019

Publication title -

aging

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.473

H-Index - 90

ISSN - 1945-4589

DOI - 10.18632/aging.102187

Subject(s) - angiogenesis , pi3k/akt/mtor pathway , cancer research , melanoma , vascular endothelial growth factor a , vegf receptors , medicine , signal transduction , biology , microbiology and biotechnology , vascular endothelial growth factor

In our previous study, kindlin-2 promoted skin wound healing and decreased the permeability of neovascularization during angiogenesis. Herein, we explored the biological function and underlying mechanism of kindlin-2 in cutaneous melanoma.

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