LINC01198 promotes proliferation and temozolomide resistance in a NEDD4-1-dependent manner, repressing PTEN expression in glioma | Zendy

Weilin Chen | Zendy; Hongjin Chen | Zendy; Guoqiang Hou | Zendy; Xiaohua Zhang | Zendy; Jianwei Ge | Zendy

Open Access

LINC01198 promotes proliferation and temozolomide resistance in a NEDD4-1-dependent manner, repressing PTEN expression in glioma

Author(s) -

Weilin Chen,

Hongjin Chen,

Guoqiang Hou,

Xiaohua Zhang,

Jianwei Ge

Publication year - 2019

Publication title -

aging

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.473

H-Index - 90

ISSN - 1945-4589

DOI - 10.18632/aging.102162

Subject(s) - pten , glioma , temozolomide , gene knockdown , cancer research , tensin , ubiquitin ligase , cell growth , biology , pi3k/akt/mtor pathway , ubiquitin , signal transduction , microbiology and biotechnology , cell culture , biochemistry , genetics , gene

Dysregulation of numerous lncRNAs has been recently confirmed in glioma; however, the majority of their roles and mechanisms involved in this notorious disease remain largely unclear. This study aims to explore the roles and molecular mechanisms of LINC01198 implicated in the proliferation and chemoresistance in glioma.

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