Down-regulation of lncRNA MALAT1 alleviates vascular lesion and vascular remodeling of rats with hypertension | Zendy

Yuzeng Xue | Zendy; Zhijuan Li | Zendy; Weitao Liu | Zendy; Jin-Jiao Shan | Zendy; Lei Wang | Zendy; Qian Su | Zendy

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Down-regulation of lncRNA MALAT1 alleviates vascular lesion and vascular remodeling of rats with hypertension

Author(s) -

Yuzeng Xue,

Zhijuan Li,

Weitao Liu,

Jin-Jiao Shan,

Lei Wang,

Qian Su

Publication year - 2019

Publication title -

aging

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.473

H-Index - 90

ISSN - 1945-4589

DOI - 10.18632/aging.102113

Subject(s) - malat1 , oxidative stress , medicine , apoptosis , notch signaling pathway , lesion , inflammation , adenocarcinoma , cancer research , endocrinology , long non coding rna , pathology , biology , downregulation and upregulation , receptor , cancer , biochemistry , gene

Recently, the effect of long non-coding RNAs (lncRNAs) in hypertension (HTN) has been identified. This study aims to explore the expression of lncRNA metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) in HTN and its role in vascular lesion and remodeling of HTN rats.

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