Open AccessGCN-5/PGC-1α signaling is activated and associated with metabolism in cyclin E1-driven ovarian cancer
Author(s) -
Ting Guo,
Bin Li,
Chao Gu,
Xiuying Chen,
Mengxin Han,
XiaoCheng Liu,
Congjian Xu
Publication year - 2019
Publication title -
aging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.473
H-Index - 90
ISSN - 1945-4589
DOI - 10.18632/aging.102082
Subject(s) - cyclin e1 , cancer research , cell cycle , cyclin e , ovarian cancer , cyclin dependent kinase 2 , biology , cell growth , acetylation , cell cycle checkpoint , cyclin , chemistry , apoptosis , cancer , biochemistry , genetics , gene
We previously found Cyclin E1-driven high grade serous ovarian cancer (HGSOC) showed metabolic shift. In this study, we aimed to elucidate signaling pathway therein.
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