Long non-coding RNA CDKN2B-AS1 reduces inflammatory response and promotes cholesterol efflux in atherosclerosis by inhibiting ADAM10 expression | Zendy

Haocheng Li | Zendy; Song Han | Zendy; Qingfeng Sun | Zendy; Ye Yao | Zendy; Shiyong Li | Zendy; Chao Yuan | Zendy; Bo Zhang | Zendy; Bao Jing | Zendy; Jia Qian Wu | Zendy; Ye Song | Zendy; Haiyang Wang | Zendy

Open Access

Long non-coding RNA CDKN2B-AS1 reduces inflammatory response and promotes cholesterol efflux in atherosclerosis by inhibiting ADAM10 expression

Author(s) -

Haocheng Li,

Song Han,

Qingfeng Sun,

Ye Yao,

Shiyong Li,

Chao Yuan,

Bo Zhang,

Bao Jing,

Jia Qian Wu,

Ye Song,

Haiyang Wang

Publication year - 2019

Publication title -

aging

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.473

H-Index - 90

ISSN - 1945-4589

DOI - 10.18632/aging.101863

Subject(s) - abcg1 , downregulation and upregulation , gene silencing , chemistry , cancer research , adam10 , biology , microbiology and biotechnology , matrix metalloproteinase , metalloproteinase , abca1 , biochemistry , gene , transporter , disintegrin

Long non-coding RNAs (lncRNAs) play key roles in the development of atherosclerosis through the inflammatory pathway. This study aimed to investigate the role of lncRNA cyclin-dependent kinase inhibitor 2B antisense RNA 1 (CDKN2B-AS1) in atherosclerosis via its function in A disintegrin and metalloprotease 10 (ADAM10).

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