FoxD2-AS1 promotes glioma progression by regulating miR-185-5P/HMGA2 axis and PI3K/AKT signaling pathway | Zendy

Wei Ni | Zendy; Yaoxiong Xia | Zendy; Yuxu Bi | Zendy; Wen Fan | Zendy; Dong Hu | Zendy; Lin Luo | Zendy

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FoxD2-AS1 promotes glioma progression by regulating miR-185-5P/HMGA2 axis and PI3K/AKT signaling pathway

Author(s) -

Wei Ni,

Yaoxiong Xia,

Yuxu Bi,

Wen Fan,

Dong Hu,

Lin Luo

Publication year - 2019

Publication title -

aging

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.473

H-Index - 90

ISSN - 1945-4589

DOI - 10.18632/aging.101843

Subject(s) - glioma , hmga2 , cancer research , pi3k/akt/mtor pathway , gene knockdown , biology , protein kinase b , long non coding rna , mtt assay , carcinogenesis , viability assay , signal transduction , cell growth , downregulation and upregulation , microrna , chemistry , apoptosis , microbiology and biotechnology , cancer , gene , biochemistry , genetics

The present study was aimed at exploring the role of long noncoding RNA (lncRNA) FOXD2-AS1 in the development and progression of glioma and the underlying mechanism of FOXD2-AS1/miR-185-5p/HMGA2 network in glioma via regulation of PI3K/Akt signaling pathway.

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