Predicting chromosome 1p/19q codeletion by RNA expression profile: a comparison of current prediction models | Zendy

Zhiliang Wang | Zendy; Zheng Zhao | Zendy; Zheng Wang | Zendy; Chuanbao Zhang | Zendy; Tao Jiang | Zendy

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Predicting chromosome 1p/19q codeletion by RNA expression profile: a comparison of current prediction models

Author(s) -

Zhiliang Wang,

Zheng Zhao,

Zheng Wang,

Chuanbao Zhang,

Tao Jiang

Publication year - 2019

Publication title -

aging

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.473

H-Index - 90

ISSN - 1945-4589

DOI - 10.18632/aging.101795

Subject(s) - cohort , oncology , medicine , glioma , chromosome , clinical practice , computational biology , bioinformatics , biology , genetics , gene , cancer research , physical therapy

Chromosome 1p/19q codeletion is increasingly being recognized as the crucial genetic marker for glioma patients and have been included in WHO classification of glioma in 2016. Fluorescent in situ hybridization, a widely used method in detecting 1p/19q status, has some methodological limitations which might influence the clinical management for doctors. Here, we attempted to explore an RNA sequencing computational method to detect 1p/19q status.

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