Open AccessRapamycin as longevity enhancer and cancer preventative agent in the context of p53 deficiency
Author(s) -
Lawrence A. Donehower
Publication year - 2012
Publication title -
aging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.473
H-Index - 90
ISSN - 1945-4589
DOI - 10.18632/aging.100494
Subject(s) - longevity , carcinogenesis , context (archaeology) , enhancer , cancer research , cancer , biology , genetics , gene , transcription factor , paleontology
Comment on: 1. Komarova et al. Rapamycin extends lifespan and delays tumorigenesis in heterozygous p53+/- mice. Aging. 2012; 4:102. Comas et al. New nanoformulation of rapamycin Rapatar extends lifespan in homozygous p53-/- mice by delaying carcinogenesis. Aging.2012; 4;10.
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