Quality and quantity control of proteins in senescence | Zendy

Masashi Narita | Zendy

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Quality and quantity control of proteins in senescence

Author(s) -

Masashi Narita

Publication year - 2010

Publication title -

aging

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.473

H-Index - 90

ISSN - 1945-4589

DOI - 10.18632/aging.100145

Subject(s) - autophagy , senescence , microbiology and biotechnology , biology , cellular senescence , downstream (manufacturing) , genetics , gene , engineering , phenotype , apoptosis , operations management

Autophagy has been implicated in aging and age-related diseases but its roles in these processes are far from straightforward: the anti-aging effect of autophagy has been shown in lower eukaryotes, and both pro- and anti-tumorigenic effects of autophagy have also been demonstrated. The new link between autophagy and senescence provides an insight into the diversified downstream effects of autophagy in various cellular contexts.

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