Statin-associated myopathy: a general overview

Among the amazing turn of events in preventing and reducing the risk of cardiovascular diseases since the discovery of statins, thousand of physicians started to prescribe it as a regular life-long treatment, but regarding the expanding number of patients on statin therapy, a wide spectrum of side effects started to appear. Statin-associated myopathy considered as one of the most common side effects and could be subtle for a long time, we performed a review to provide a clinical summary of statin-associated myopathy and to discuss possible mechanisms of risk factors and management of statin-associated myopathy.