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The extraction of Lavandula Officinalis (lavender) and Hypericum Perforatum (centaury) plants grown in Mersin region were extracted by supercritical carbondioxide extraction system (P=100 bar, T=40 o C). The chemical composition of the lavender and centaury extracts were analysed by Gas Chromatography–Mass Spectrograph (GC-MS). For antioxidant activity experiments, 1,1-diphenyl-2-pycrylhidrazine (DPPH) radical was used in radical effect tests. For antimicrobial activity studies, Bacillussubtilis, Klebsiellapneumoniae, Escherichiacoli, Staphylococcusaureus, Pseudomonasaeruginosa and Streptococcuspneumoniae with Nutrient Agar Broth (NA) and Eosin Methylene-blue lactose sucrose agar (EMB) broth were used. For determining antimicrobial effect of plant extracts, diffusion method was used. Antibacterial and antioxidant properties of the obtained extracts were examined and have been determined that the resulting extracts have significant antioxidant and antimicrobial effect. The extracts were also used in cosmetic cream formulas as protectives. Effective results have also been determined in antibacterial activity studies of creams after 6 months.

journal of the turkish chemical society, section a: chemistry

Supercritical Carbondioxide Extraction of Lavandula Officinalis (Lavender) and Hypericum Perforatum (Centaury) Plants Grown in Mersin Region: Investigation of Antioxidant and Antibacterial Activities of Extracts and Usage as Cosmetic Preservatives in Creams