CSA Catalyzed Multi-component Synthesis of Polycyclic Pyrazolo[4,3-e]pyridines Under Ultrasonic Irradiation and Their Antioxidant Activity
Author(s) -
Emel Pelit
Publication year - 2017
Publication title -
journal of the turkish chemical society section a chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.179
H-Index - 6
ISSN - 2149-0120
DOI - 10.18596/jotcsa.295465
Subject(s) - chemistry , catalysis , amine gas treating , camphor , antioxidant , sulfonic acid , component (thermodynamics) , organic chemistry , medicinal chemistry , nuclear chemistry , thermodynamics , physics
New fused pyrazolo[4,3-e]pyridines were obtained by multi-component reaction of 1,3-dimethyl-1 H -pyrazol-5-amine or 3-phenyl-1 H -pyrazol-5-amine, aromatic aldehydes and indan-1,3-dione in the presence of camphor-10-sulfonic acid (CSA) as an effective catalyst under ultrasound promoted conditions. The antioxidant activity of the pyrazolopyridine compounds 4b , 5c , 5e , 7a , 7b and 7c were determined.
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