SYNTHESIS, CHARACTERIZATION AND ANTIOXIDANT ACTIVITIES OF NOVEL 1-(MORPHOLINE-4-YL-METHYL)-3-ALKYL(ARYL)-4-[4-(DIMETHYLAMINO)-BENZYLIDENAMINO]-4,5-DIHYDRO-1H-1,2,4-TRIAZOL-5-ONES | Zendy

Özlem Gürsoy Kol | Zendy; Haydar Yüksek | Zendy; Sevda Manap | Zendy; Feyzi Sinan Tokalı | Zendy

Open Access

SYNTHESIS, CHARACTERIZATION AND ANTIOXIDANT ACTIVITIES OF NOVEL 1-(MORPHOLINE-4-YL-METHYL)-3-ALKYL(ARYL)-4-[4-(DIMETHYLAMINO)-BENZYLIDENAMINO]-4,5-DIHYDRO-1H-1,2,4-TRIAZOL-5-ONES

Author(s) -

Özlem Gürsoy Kol,

Haydar Yüksek,

Sevda Manap,

Feyzi Sinan Tokalı

Publication year - 2016

Publication title -

journal of the turkish chemical society section a chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.179

H-Index - 6

ISSN - 2149-0120

DOI - 10.18596/jotcsa.23635

Subject(s) - morpholine , chemistry , alkyl , aryl , proton nmr , antioxidant , formaldehyde , chelation , carbon 13 nmr , organic chemistry , stereochemistry , medicinal chemistry

In this paper, eight novel 1-(morpholine-4-yl-methyl)-3-alkyl(aryl)-4-[4-(dimethylamino)-benzylidenamino]-4,5-dihydro-1H-1,2,4-triazol-5-ones ( 2 ) were obtained by the reactions of 3-alkyl(aryl)-4-[4-(dimethylamino)-benzylidenamino]-4,5-dihydro-1H-1,2,4-triazol-5-ones ( 1 ) with formaldehyde and morpholine. The novel synthesized compounds were identified by IR, 1 H NMR and 13 C NMR spectral data. Besides, the newly synthesized compounds were analysed for their in vitro potential antioxidant capacities in three different assays. All of the compounds demonstrated significant activity for metal chelating effect.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research