Iron overload.

Iron overload occurs when excess iron accumulates in the body. Those receiving iron therapy are vulnerable to iron overload as we lack major mechanisms for iron excretion (minor ones are cell desquamation and occult blood loss). Excess iron is deposited in body organs (the heart, liver and endocrine glands in particular), causing organ damage. Probably, iron saturates the liver first and then accumulates in other organs [1] .