Timolol maleate.

Timolol Maleate ophthalmic solution is a non-selective beta-adrenergic receptor blocking agent. Its chemical name is (-)-1-(tert-Butylamino)-3-[(4-morpholino-1,2,5-thiadiazol-3-yl)oxy]-2-propanol maleate (1:1) (salt). Timolol Maleate possesses an asymmetric carbon atom in its structure and is provided as the levo-isomer. The nominal optical rotation of Timolol Maleate is: 25° [α] in 1.0N HCl (C = 5%) = -12.2° (-11.7 to -12.5°). 405 nm Its molecular formula is C13 H24 N4 O3 S • C4 H4 O4 and its structural formula is: