Cerebriform Nevus Sebaceous in a Newborn Infant

Nevus sebaceous is a hamartoma of the skin and its adnexa. Cerebriform nevus sebaceous is a morphological variant commonly seen in newborn infants over the scalp as large, pedunculated or verrucous, hairless plaques. Most lesions are isolated but some may be associated with other systemic abnormalities including CNS, cardiovascular, ocular and urological involvement. Most lesions are benign but there is a very small chance of malignant transformation especially when they grow during puberty and hence biopsy should be done in all cases and if possible complete excision. We describe a newborn infant with cerebriform nevus sebaceous of the scalp with no other systemic abnormalities. The lesion was excised completely and biopsy showed no evidence of malignant potential.