Generalized exfoliative skin rash as an early predictor of supratherapeutic voriconazole trough levels in a leukemic child: A case report | Zendy

Ali Amanati | Zendy; Parisa Badiee | Zendy; Mehrzad Lotfi | Zendy; Ahmad Monabati | Zendy; Mohammad Ali Faghihi | Zendy; Majid Yavarian | Zendy; Nazafarin Hatami Mazinani | Zendy

Open Access

Generalized exfoliative skin rash as an early predictor of supratherapeutic voriconazole trough levels in a leukemic child: A case report

Author(s) -

Ali Amanati,

Parisa Badiee,

Mehrzad Lotfi,

Ahmad Monabati,

Mohammad Ali Faghihi,

Majid Yavarian,

Nazafarin Hatami Mazinani

Publication year - 2020

Publication title -

current medical mycology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.369

H-Index - 6

eISSN - 2423-3439

pISSN - 2423-3420

DOI - 10.18502/cmm.6.3.4500

Subject(s) - medicine , voriconazole , dermatology , rash , caspofungin , toxic epidermal necrolysis , erythroderma , antifungal

Skin rashes, mostly seen in children and adolescents, are considered among the most common side effects of azole antifungals. Although therapeutic concentrations of voriconazole (VCZ) have been documented for infected skin, there is no evidence specifying whether specific dermatologic side effects could predict high VCZ serum concentration, especially in high-risk leukemic children.

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