An update on the application of nano-scaled carriers against fluconazole-resistant Candida species: nanostructured lipid carriers or solid lipid nanoparticles? | Zendy

Maryam Moazeni | Zendy; Majid Saeedi | Zendy; Hamidreza Kelidari | Zendy; Mojtaba Nabili | Zendy; Amirhossein Davari | Zendy

Open Access

An update on the application of nano-scaled carriers against fluconazole-resistant Candida species: nanostructured lipid carriers or solid lipid nanoparticles?

Author(s) -

Maryam Moazeni,

Majid Saeedi,

Hamidreza Kelidari,

Mojtaba Nabili,

Amirhossein Davari

Publication year - 2019

Publication title -

current medical mycology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.369

H-Index - 6

eISSN - 2423-3439

pISSN - 2423-3420

DOI - 10.18502/cmm.5.4.1965

Subject(s) - fluconazole , solid lipid nanoparticle , antifungal , sonication , azole , chemistry , nanoparticle , pharmacology , drug delivery , materials science , nanotechnology , chromatography , microbiology and biotechnology , biology , organic chemistry

Encapsulation can lead to improved efficacy and safety of antifungal compounds. The attention of scientists has recently turned to biocompatible lipids as the carriers for the delivery of antifungal drugs, such as fluconazole. Although several research reports have already been published on fluconazole loaded solid lipid nanoparticles (FLZ-SLNs) and fluconazole loaded nanostructured lipid carriers (FLZ-NLCs), the possible advantages of NLCs over SLNs have not yet been fully established. Studies performed so far have given several contradictory results.

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