Evaluation of biofilm formation in the homozygous and heterozygous strains of vaginal Candida albicans isolates | Zendy

Keyvan Pakshir | Zendy; Sahar Sheykhi | Zendy; Kamiar Zomorodian | Zendy; Hasti Nouraei | Zendy; Zahra Zare Shahrabadi | Zendy

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Evaluation of biofilm formation in the homozygous and heterozygous strains of vaginal Candida albicans isolates

Author(s) -

Keyvan Pakshir,

Sahar Sheykhi,

Kamiar Zomorodian,

Hasti Nouraei,

Zahra Zare Shahrabadi

Publication year - 2019

Publication title -

current medical mycology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.369

H-Index - 6

eISSN - 2423-3439

pISSN - 2423-3420

DOI - 10.18502/cmm.5.2.1160

Subject(s) - biofilm , candida albicans , microbiology and biotechnology , corpus albicans , biology , heterozygote advantage , gene , locus (genetics) , genotype , bacteria , genetics

Candida albicans is one of the most opportunistic yeasts around the world. This species has two heterozygous and homozygous strains at hyphal wall protein 1 ( hwp1 ) gene locus. A simple method for the discrimination of these two strains is the amplification of HWP1 gene. Regarding this, the aim of this study was to discriminate C. albicans heterozygous and homozygous strains via the amplification of hwp1 gene and evaluation of biofilm formation between the strains.

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