Cellular apoptosis: An alternative mechanism of action for caspofungin against Candida glabrata | Zendy

Parisa Aryamloo | Zendy; Hossein AsgarianOmran | Zendy; Narges Aslani | Zendy; Hadi HosseinNataj | Zendy; Tahereh Shokohi | Zendy; Hamid Badali | Zendy; Mojtaba Nabili | Zendy; Atefeh Abdollahi Gohar | Zendy; Maryam Moazeni | Zendy

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Cellular apoptosis: An alternative mechanism of action for caspofungin against Candida glabrata

Author(s) -

Parisa Aryamloo,

Hossein AsgarianOmran,

Narges Aslani,

Hadi HosseinNataj,

Tahereh Shokohi,

Hamid Badali,

Mojtaba Nabili,

Atefeh Abdollahi Gohar,

Maryam Moazeni

Publication year - 2019

Publication title -

current medical mycology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.369

H-Index - 6

eISSN - 2423-3439

pISSN - 2423-3420

DOI - 10.18502/cmm.5.2.1155

Subject(s) - caspofungin , propidium iodide , apoptosis , necrosis , biology , programmed cell death , microbiology and biotechnology , annexin , pharmacology , biochemistry , fluconazole , antifungal , genetics

Although the mechanism of action for echinocandins is known, the physiological mechanisms by which these antifungal agents cause cell death via the classical apoptotic pathways are not well-defined yet. Regarding this, the present study aimed to evaluate the mechanisms of caspofungin-induced Candida glabrata cell death.

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