SRPX2 promotes cell proliferation and invasion via activating FAK/SRC/ERK pathway in non-small cell lung cancer | Zendy

Xiujuan Li | Zendy; Jing Liu | Zendy; Hong Sun | Zendy; Yong Zou | Zendy; Juan Chen | Zendy; YiChun Chen | Zendy; Cheng Chen | Zendy; Xuan Wu | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

SRPX2 promotes cell proliferation and invasion via activating FAK/SRC/ERK pathway in non-small cell lung cancer

Author(s) -

Xiujuan Li,

Jing Liu,

Hong Sun,

Yong Zou,

Juan Chen,

YiChun Chen,

Cheng Chen,

Xuan Wu

Publication year - 2020

Publication title -

acta biochimica polonica

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.452

H-Index - 78

eISSN - 1734-154X

pISSN - 0001-527X

DOI - 10.18388/abp.2020_5158

Subject(s) - cell growth , cell migration , cancer research , gene knockdown , epithelial–mesenchymal transition , cell , mapk/erk pathway , immunohistochemistry , metastasis , a549 cell , western blot , downregulation and upregulation , proto oncogene tyrosine protein kinase src , cell culture , lung cancer , cancer , chemistry , biology , pathology , signal transduction , microbiology and biotechnology , medicine , biochemistry , genetics , gene

Recent studies showed that sushi repeat containing protein X linked 2 (SRPX2) could participate in the development of various malignant tumors. However, its role in non-small cell lung cancer (NSCLC) was unknown. The aim of the study was to prospectively investigate the role of SRPX2 in NSCLC cell proliferation, migration and invasion and reveal the underlying mechanism.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research