Is it possible to predict a risk of osteoporosis in patients with juvenile idiopathic arthritis? A study of serum levels of markers of bone turnover | Zendy

Marta Janicka-Szczepaniak | Zendy; Krzysztof Orczyk | Zendy; Katarzyna Szymbor | Zendy; Danuta ChlebnaSokół | Zendy; Elżbieta Smolewska | Zendy

Open Access

Is it possible to predict a risk of osteoporosis in patients with juvenile idiopathic arthritis? A study of serum levels of markers of bone turnover

Author(s) -

Marta Janicka-Szczepaniak,

Krzysztof Orczyk,

Katarzyna Szymbor,

Danuta ChlebnaSokół,

Elżbieta Smolewska

Publication year - 2018

Publication title -

acta biochimica polonica

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.452

H-Index - 78

eISSN - 1734-154X

pISSN - 0001-527X

DOI - 10.18388/abp.2017_2561

Subject(s) - osteoprotegerin , bone remodeling , medicine , osteoporosis , osteocalcin , bone mineral , endocrinology , alkaline phosphatase , receptor , activator (genetics) , biology , biochemistry , enzyme

Low bone mineral density is a common finding in children with systemic connective tissue diseases, including juvenile idiopathic arthritis (JIA). The influence of the ongoing process of bone remodeling on the disease course merits further investigation. The aim of this study was to assess the clinical relevance of markers of bone turnover and their potential role as predictors of higher fracture risk and, by extension, risk of osteoporosis.

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